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Collection IPCM-CHEMBIO
L’équipe Chembio conçoit et synthétise des hétérocycles et des complexes organométalliques de métaux de transition pour des applications en chimie médicinale (cancer, maladies neurodégénératives) et (bio)analyse (sondes IR et luminescentes).
Dernières publications
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Edwyn Remadna, Anna Wilsmann, Nicolas Stadler, Jérémy Forté, Nadia Hoyeau, et al.. Synthesis and Biological Evaluation of a New Biphenyl-Based Organogold(III) Complex with In Vitro and In Vivo Anticancer Activity. Journal of Medicinal Chemistry, In press, ⟨10.1021/acs.jmedchem.4c02470⟩. ⟨hal-04883531⟩
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Robin Ramos, Anthi Karaiskou, Candice Botuha, Sadek Amhaz, Michaël Trichet, et al.. Identification of Cellular Protein Targets of a Half-Sandwich Iridium(III) Complex Reveals Its Dual Mechanism of Action via Both Electrophilic and Oxidative Stresses. Journal of Medicinal Chemistry, 2024, 67 (8), pp.6189-6206. ⟨10.1021/acs.jmedchem.3c02000⟩. ⟨hal-04537800⟩